Welcome to the Weinacht Lab, where we study hematopoiesis and immune system development in the context of specific, clinically relevant genetic defects. A physician-scientist with formal training in hematology/oncology/stem cell transplantation and a never-ending fascination with the immune system, I have always been captivated by inborn errors in immunity and hematopoiesis.
Our team focuses on solving the molecular puzzles that underly rare diseases to shed light on fundamental principles governing hematopoiesis and immune system development. Our goal is to find better therapies for patients. We are a young and dynamic group driven by excitement for scientific discovery. Our lab is home to a mindset of growth and possibility. Curious? Come check us out…
The Weinacht Laboratory has an opening for a highly motivated and collaborative postdoctoral fellow with interest in hematopoiesis and thymic development. Successful candidates will join the Pediatric Division of Stem Cell Transplantation and Regenerative Medicine at Stanford University School of Medicine.
The project will focus on understanding and recreating a bone marrow stromal and thymic stromal microenvironment using pluripotent stem cells. Our laboratory has used single-cell transcriptomics of primary human fetal thymic tissues to develop a robust in vitro and in vivo developmental model of thymic development.
This model can now be applied to differentiating iPSCs into regenerative thymic tissues for clinical translation and studying thymic development in clinically relevant disease-specific contexts. The in vitro differentiation of iPSCs into thymic epithelial cell fate is a well-established platform in our lab. Our team is looking for a new postdoc to focus on studying early bone marrow stromal commitment.
PhD or MD/PhD applicants with background in developmental/cell biology, immunology, or molecular biology with the following qualifications are encouraged to apply:
- Strong tissue culture skills; experience in iPSC culture desirable
- Flow cytometry skills
- Good understanding of emerging molecular and cell biology tools
- Outstanding personal initiative and communication skills.
- Academic aspirations
- Updated CV
- Complete contact information for three references
- Cover letter describing their past research experience, career goals, and a statement of future research interest (1-2 pages)
