Job Description
This postdoctoral position is dedicated to studying autophagy functions in glia for breast cancer brain metastasis. The Wang laboratory also focuses on the functions and mechanisms of selective autophagy and lipid metabolisms in neural stem cells, microglia, and astrocytes. The lab developed novel genetically engineered mouse models to study roles of autophagy genes in brain developmental and in progress of breast cancer brain metastasis. We use a variety of techniques including single cell RNA-seq, single nuclei RNA-seq, single cell lineage tracing, human iPSC derived cerebral organoids, chemogenetics, clarity technique, patch clamp, super-resolution images, metabolic/molecular/cellular approaches to gain insights in autophagy’s functions in human developmental disorders and breast cancer brain metastasis.
Required Education
Doctoral Degree in the appropriate field or discipline, or the recognized terminal degree, or the equivalent foreign equivalent.
Preferred Experience
At least one year of experience in neuroscience research, cell and molecular biology, or cancer biology.
Additional Qualifications Considered
- Experience in neural stem cell, cancer biology, signal transduction, metabolism, autophagy, glia cells, organoids, and genetic mouse models.
- Experience in scRNAseq and snRNAseq is ideal.
- Good oral and written communication skills.
- Ability to work and collaborate effectively with students, faculty and staff from a variety of culturally diverse backgrounds.
Additional Information:
The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nation’s largest and most comprehensive public universities and a top employer in Ohio.
As one of only 54 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies – providing tomorrow’s standard of care today. A Cancer-Free World Begins Here.
Hiring Range:
NIH rate starts at $61,008 per year.
Location:
Tzagournis Medical Research Facility (0163)
Position Type:
Term (Fixed Term)
Scheduled Hours:
40
Shift:
First Shift
Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.
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The university is an equal opportunity employer, including veterans and disability.
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