The Cellular Therapy Lab (CTL) at Fred Hutch is on the cutting edge of new technologies for cancer therapy, including cell-based immunotherapy. We are committed to advancing treatment options for our patients through the translation of innovative research into clinical practice. We collaborate with our Alliance members (University of Washington, Fred Hutchinson Cancer Research Center and Seattle Children’s Hospital) as well as corporate entities.
CTL is responsible for all minimally manipulated therapeutic cell processing occurring at Fred Hutch. Procedures range from cryopreservation to flow cytometric enumeration of cell proportions to more complex procedures such as cell selection, enrichment, and depletion. The laboratory is regulated by the FDA cGTP/cGMP standards, maintains CAP certification, and is accredited by the Joint Commission and FACT.
Responsibilities
- Process cellular products/specimens according to standard operating procedure (SOP) and specific guidance for clinical trials using aseptic technique
- Perform and analyze results of quality control testing of components, including automated nucleated cell counts and flow cytometry
- Document processing steps accurately, generate processing reports and prepare patient/donor laboratory charts; review processing reports and charts
- Understand and stay current with SOPs as needed, and perform SOP qualifications. Provide input/feedback to Lab Supervisor on documentation and process improvements
- Participate in the training process of newer, less experienced Technologists
- Perform competency assessments as applicable
- Thaw cryopreserved components and assist with infusion at the patient bedside
- Meet unrelated donor (URD) component couriers and perform necessary testing and processing of components prior to release
Perform special processing:
- CliniMACS® cell selection e.g. CD34+ cell enrichment, CD3+ cell depletion
- Potentially assist with the bone marrow collection within operating room
Qualifications
Required:
- Four-year college degree with major in medical technology or biological sciences required
- 2+ years clinical cell therapy experience
- Basic hematology knowledge
- Motivation and initiative to learn new scientific theory and applications
- Mature judgment
- Work independently with regular review of progress and results
- Proven team player
- Collaborate and communicate effectively across functions
- Interpret data thoroughly
- Strong trouble-shooting capabilities
- Scientific writing skills, including preparation of clear, concise SOPs and technical reports
- Strong math skills
- Strong communication skills
- Attention to detail
- Flexibility in scheduling: night, weekend and holiday rotations
Preferred:
- Flow cytometry expertise
- Immunotherapy experience
- CliniMACS® operation experience
- LabWare, LIMS knowledge
- A good understanding of cGMP/cGTP standards
- Knowledge of FDA, FACT and CAP regulations.
- Valid Washington State driver’s license strongly preferred.
A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.
The hourly pay range for this position is from $38.67 to $57.99 and pay offered will be based on experience and qualifications.
