About the Position
The Lee laboratory at the Fox Chase Cancer Center is recruiting highly ambitious and self-motivated Postdoctoral Fellows. The Lee laboratory focuses on computational epigenetics in cancer and aging. We are interested in identifying somatic epi-mutations in early-stage cancer and molecular-level subtypes using comprehensive multi-omics data analysis. The objective is to optimize clinically actional biomarkers and develop machine learning models to predict cancer typing, subtyping, matching therapeutics, and predicting relapse or metastasis.
We pursue cutting-edge technologies, including long-read sequencing technology, cell-free DNA, single-cell multi-omics data, single-cell spatial transcriptomics, and proteomics data. Computationally we adopt deep learning and more interpretable machine learning algorithms to model epigenetic and image signatures for early diagnosis, recommend therapeutic options, and predict their prognostic prospects in cancer. Some example publications addressing these areas of interest are Lee et al.(2012) Bioinformatics, Lee et al. (2020) Nat Commun, and Lee et al. (2021) Mathematical and Computational Oncology.
The Lee laboratory seeks candidates that published peer-reviewed manuscripts and that have strong expertise in cancer biology, computational medicine, and epigenomics. The experience and skills in High-performance computing (HPC), Slurm job management, Python, and R will be welcome. Additional details regarding the laboratory research can be found at https://comp-epi-lee-lab.org/.
About the Training Environment
As one of the four original cancer centers to receive comprehensive designation from the National Cancer Institute, Fox Chase Cancer Center has been at the forefront of cancer research for almost 90 years. We are home to excellent research facilities, top clinicians and scientists, and outstanding patient care. Our singular focus on cancer, which couples discovery science with state of the art clinical care and population health, remains the foundation of our work.
The scientist training programs at Fox Chase Cancer Center provide professional development opportunities in four core areas identified as crucial for successful careers in science, research, and health care including communication, leadership, teaching, and mentorship. Upon joining the program, graduate students and postdocs develop individual development plans to help guide their growth. Training throughout the year is supplemented with free professional development opportunities, including a robust ‘How To’ series, writing courses, networking, mentorship, and teaching opportunities, a trainee-led seminar series, a trainee-led annual Research Conference, and more. Postdocs at Fox Chase Cancer Center are supported by the Temple University Postdoc Association and the Office of Academic Affairs at Fox Chase, and are compensated with competitive pay and benefits.
In addition to the robust training program, scientists at Fox Chase Cancer Center benefit from being part of the rich scientific and biotech environment in the Philadelphia region. Many of our former trainees are now employees (and contacts) at nearby institutions and companies, including The Wistar Institute, Merck, GSK, AACR, and numerous others.
To Apply
Email a CV, a cover letter that states research interest(s) and goals, and the name of at least three references to Hayan.Lee@fccc.edu. Qualified candidates will then be invited to complete a job application.
