The Sheehan lab is a translational research lab focused on developing new therapies for individuals with sickle cell disease. We are seeking an individual to perform experiments in a humanized mouse model and analyze the changes in red cells and other blood cells as a result of base editing or other gene therapies. Experience with complex, fragile mouse models and cell culture essential.
The job entails performing a variety of defined research and laboratory tests and experiments according to prescribed protocols and assigned schedules under general supervision. Experiments will be designed in collaboration with the principal investigator.
The candidate will maintain records, files and logs of work performed in laboratory notebooks and computer databases, and perform simple statistical analyses with guidance, compile data and records results of studies for publications, grants and seminar presentations. Handling of human blood samples is required; proof of immunization is required and potentially additional immunizations may be needed.