Job Description
The University of Miami/UHealth Department of SCCC has an exciting opportunity for a Full Time Post Doctoral Associate to work at the UHealth medical campus in Miami, Fl.
CORE JOB SUMMARY
The Post Doctoral Associate performs scientific research and studies under the supervision of managing staff. Moreover, the Post Doctoral Associate promotes institutional recognition through literal contributions to the scientific community.
CORE JOB FUNCTIONSÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â
Conducts research on specific areas of study as assigned. Prepares research reports and technical papers for publishing. Investigates the feasibility of applying a wide variety of scientific principles and theories. Maintains substantial knowledge of state-of-the-art principles and theories. Develops advanced analytical models and systems and provides solutions and analyses to support strategic and tactical decisions. Adheres to University and unit-level policies and procedures and safeguards University asset
This list of duties and responsibilities is not intended to be all-inclusive and may be expanded to include other duties or responsibilities as necessary.
CORE QUALIFICATIONSÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â
Education:
- Ph.D. in biochemistry, chemistry, molecular biology or another relevant field required
Experience:
no experience required
Knowledge, Skills and Attitudes:
- Has the appropriate expertise in discovery of molecular, biochemical or chemical mechanisms; and is highly driven.
- Outstanding verbal and communication skills are required.
- Skill in collecting, organizing, and analyzing data.
- Ability to recognize, analyze, and solve a variety of problems.
- Ability to exercise sound judgment in making critical decisions.
Department Specific Functions
Our laboratory focuses on mechanistic discovery to understand the metabolic and molecular mechanisms of androgen synthesis and androgen receptor gain-of-function that lead to resistance to hormonal therapy. Our work is revealing fundamental endocrine mechanisms in both normal physiology and disease, including stress, aging, and glucocorticoid resistance, that will lead to broad applications to oncology and cancer physiology.
Specific areas include:
- Metabolic and genetic changes required for hormone therapy resistance in prostate and breast cancers
- Discovery of entirely new mechanisms of endocrine physiology and regulation
- Clinical validation in patients and clinical trials using innovative approaches
- Animal models of advanced cancer for translational and therapeutic studies
- Identifying targets for the development of new pharmacologic therapies
- Drug discovery for new therapies
The Desai Sethi Urology Institute at the University of Miami Miller School of Medicine is seeking to recruit a postdoctoral associate to lead the development and implementation of Mass Spectrometry applications for translational and clinical research. The postdoc will partner with principal investigators and an outstanding clinical urology team with the goal of defining the underlying biochemical and clinical behavior genitourinary disorders to identify new strategies that will lead to durable clinical benefits. This position will provide a unique and multidisciplinary exposure to tumor metabolism, molecular oncology, drug development, and clinical trials.
Department Specific Qualifications                                                                                    Â
Ability to lead MS based projects with minimal oversight. Proficient in basic statistical methods and design of MSI / LC-MS experiments and techniques. 2+ years of relevant experience in a research or laboratory environment including: Working knowledge of MSI / LC/MS instrumentation, operation, maintenance, and troubleshooting (Experience with AB Sciex/Agilent Systems Preferred). Hands-on experience with sample preparation and extraction of small molecules from various biological matrices. Knowledge of various extraction protocols (protein precipitation, liquid-liquid extraction, solid phase extraction, etc.). Hands-on experience with different chromatographic separation and mass spectrometry methodologies for analysis of biomarkers, or small molecules.
