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What is Mitosis

o Mitosis is nuclear division without genetic change, and results in genetically identical daughter cells,

o Mitosis varies among eukaryotes.

o For instance, fungi don’t have centrioles (prokaryotes and plants don’t either) and never lose their nuclear membranes.

o Mitosis occurs in both haploid and diploid cells.

o Prokaryotes don’t undergo mitosis or meiosis!!

Diagram of Mitosis Phases

Mitosis vs Meiosis, Mitosis vs Meiosis Chart, Mitosis Diagram, difference between mitosis and meiosis

Stages of Mitosis

i. Prophase

o Condensation of chromatin into chromosomes occurs.

o Centrioles move to opposite ends of the cells.

o First the nucleolus and then the nucleus disappear.

o The spindle apparatus begins to form consisting of aster (microtubules radiating from the centrioles), kinetochore microtubules growing from the centromeres (a group of proteins located toward the center of the chromosome), and spindle microtubules connecting the two centrioles.

o The kinetochore is a structure of protein and DNA located at the centromere of the joined chromatids of each chromosome.

o The centromere allows one copy of each chromatid to be apportioned to each daughter cell

ii. Metaphase

o Chromosomes line up along the equator of the cell.

3) Anaphase – begins when the sister chromatids split at their attaching centromeres, and move toward opposite ends of the cell. This split is termed disjunction!!! Cytokinesis, the actual separation of the cellular cytoplasm due to constriction of microfilaments about the center for the cell, may commence toward the end of this phase. 4) Telophase – The nuclear membrane reforms followed by the reformation of the nucleolus. Chromosomes decondense and cytokinesis continues.

Remember that mitosis results in genetically identical daughter cells since its asexual reproduction!!

iii. Anaphase

o Anaphase begins when the sister chromatids split at their attaching centromeres, and move toward opposite ends of the cell.

o This split is termed disjunction.

o Cytokinesis, the actual separation of the cellular cytoplasm due to constriction of microfilaments about the center for the cell, may commence toward the end of this phase.

4) Telophase – The nuclear membrane reforms followed by the reformation of the nucleolus. Chromosomes decondense and cytokinesis continues.

Remember that mitosis results in genetically identical daughter cells since its asexual reproduction!!

iv. Telophase

o The nuclear membrane reforms followed by the reformation of the nucleolus.

o Chromosomes decondense and cytokinesis continues.

o Remember that mitosis results in genetically identical daughter cells since its asexual reproduction.

Mitosis Citations

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